Don't install Windows 10 on the Intel Optane Memory module. If you plan to install both a hard drive and Intel® Optane™ Memory, Windows® 10 must be installed on the hard drive. If your Intel NUC model isn't listed in this table, there are no additional special instructions and you can proceed directly to the installation steps. See the table for special information you should know before you begin installing the operating system.
See the Supported Operating Systems for Intel® NUC Products for a list of Windows* versions supported by your Intel® NUC.